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Friday, May 13th, 1:00 pm (PST) -- pizza provided! Hosted in-person in ESB 1001 and via Zoom Bio – Alexa Hudnut is an Optical Systems Engineer at Illumina in San Diego. Her research background is true to a Biomedical Engineer – a little bit of everything. She started her research in molecular biology and gene editing and then worked her way to instrumentation design and optics. She graduated with a PhD in Biomedical Engineering from the University of Southern California in 2018. She is most passionate about creating medical devices that leverage Optics and Materials Science for an intentionally sustainable future. Abstract – Illumina’s mission is to improve human health by unlocking the power of the genome. This translates to efforts such as tracking COVID variants, determining your dog’s breed, population genomics, and everything in between. Next generation sequencing (NGS) relies heavily on epifluorescence microscopy as the backbone of instrumentation. As we look toward the future of gene sequencing, it will become more prevalent as an in vitro diagnostic (IVD). To improve the clinical workflow, increased throughput is necessary for quicker turnaround times. These improvements are being driven by innovations such as structured illumination, multiplexing, image processing, and nanofabrication.
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